Still anti-medicine?

Still anti-medicine?

There are some people that comment that modern medicine is bad. Certainly it isn’t perfect; nothing is. To say that it is all bad is silly, in my opinion. For the anti-vaxxers, there’s a whole list of diseases that we’ve eradicated due to vaccinations. The NPR piece linked helps drive home the point.

A change came when, in 1995, the first triple-drug combinations became available, Lennox says. He saw an amazing transformation take place, where people who were on their deathbed were discharged within a month.

“It was the most amazing thing and it still is,” he says. “We still get people who come in at the end stages of AIDS and if we catch them in time, many of them are restored to normal health.” [Dr. Jeffrey Lennox]

#ScienceEveryday  when it isn’t #ScienceSunday  

#Anti_anti_intellectualism

http://www.npr.org/2012/07/22/157199216/testing-treatment-key-weapons-in-aids-fight

Rhubarb poisoning not from a rube

Rhubarb poisoning not from a rube

Some time ago, ScienceSunday shared a collaborative post about potato poisoning. http://goo.gl/80fdM  Taking a break from my imaging posts here’s some information about rhubarb toxicity.

When we first planted our rhubarb in the garden we were told not to eat it for the first year, as the oxalate levels are higher in the first year. After that, the stalks are safe to eat but the leaves can have enough oxalates to make you sick. You would have to eat a lot of rhubarb to actually die from oxalate poisoning.

From  http://www.rhubarbinfo.com/poison/ 

The biodynamic (toxicity) mechanism by which oxalic acid works is somewhat different from organic poisons and is more analogous to heavy metal poisoning. Organic poisons often work through at the biochemical level, e.g. cyanide by interfering with respiration at the cellular level, strychnine by screwing up inter-synaptic transmission. There are many molecular substances in foods which offer no nutritional benefit, and must be processed and excreted. Oxalic acid, for example, is excreted in the urine, and its crystals are commonly found in microscopic urinalysis. Too much oxalic acid in the urine will result in kidney or bladder stones. Calcium combines with oxalic acid to form the less soluble salt, calcium oxalate, which is also found in kidney stones. Plant leaves, especially rhubarb, cabbage, spinach, and beet tops, contain oxalic acid. Oxalic acid is also found in potatoes and peas. Vitamin C is metabolized to oxalic acid; it contributes to over-saturation of the urine with crystals and possibly to stone formation.

The first two images are oxalate crystals. The 3rd is a microscopic image of a rhubarb leaf. The last two are the rhubarb from my garden and the rhubarb pie my wife made, respectively.

For #ScienceSunday  curated by Allison Sekuler Rajini Rao Robby Bowles and me.

I leave you with Crystal Blue Persuasion.

Tommy James & the Shondells Crystal Blue Persuasion

Edit Rajini Rao reminded me: happy π approximation day (7/22)

Uncovering Merle

Uncovering Merle

Normally my dog’s paw pads are dark, i.e. dirty. They’re not dirty in the sense that she marks the floor everywhere she walks. We just can’t scrub her paws every time we take her out. So after her swim, I figured it would be a good chance to take a photo so you can see what is Merle in dog paw pads.

Merle is a coat pattern in dogs, not a color of coat. It can affect their paw pad color, as shown in my dog below. Merle is not to be confused with heterochromia, which is specific to the eyes.   http://goo.gl/K4Djj

Merle is actually a heterozygote of an incompletely dominant gene. If two such dogs are mated, on the average one quarter of the puppies will be “double merles”. A phantom merle is one with such small patches of merle—or none at all—that it appears to be a non-merle. In America, a dog with the phantom merle coloring is described as being “cryptic for merle.”

http://goo.gl/qaNfv

Read more in the Wiki: http://en.wikipedia.org/wiki/Merle_(coat_colour_in_dogs) 

#ScienceSunday  curated by Allison Sekuler Rajini Rao Robby Bowles and me.

the idea of the contradiction comes from what I see as the deepest misunderstanding about science, which is the idea…

the idea of the contradiction comes from what I see as the deepest misunderstanding about science, which is the idea that science is about certainty.

Because obviously it’s easy to suggest that the earth sort of floats in nothing, but then you have to answer the question: why doesn’t it fall? The genius of Anaximander was to answer this question. We know his answer, from Aristotle, from other people. He doesn’t answer this question, in fact. He questions this question. He says why should it fall? Things fall toward the earth. Why the earth itself should fall? In other words, he realizes that the obvious generalization from every small heavy object falling, to the earth itself falling, might be wrong. He proposes an alternative, which is that objects fall towards the earth, which means that the direction of falling changes around the earth. […]

…what is being challenged at every step is not the theory, it’s the conceptual structure used in constructing theories and interpreting the data. In other words, it’s not changing theories that we go ahead, but changing the way we think about the world. […]

Science is not about certainty. Science is about finding the most reliable way of thinking, at the present level of knowledge. Science is extremely reliable; it’s not certain. In fact, not only it’s not certain, but it’s the lack of certainty that grounds it. Scientific ideas are credible not because they are sure, but because they are the ones that have survived all the possible past critiques, and they are the most credible because they were put on the table for everybody’s criticism. […]

Like João Figueiredo I was tempted to keep quoting the article. It’s simply a fantastic read. I come across some of the ideas/comments presented in the article when anti-science people comment on my posts or friend’s posts. At first glance, the anti-science people might find support in this article. However, if you read the whole thing, what he says at the end resonates with me and hopefully with other pro-science advocates.

#ScienceEveryday   curated by ScienceSunday (Allison Sekuler Rajini Rao Robby Bowles and me)

Originally shared by João Figueiredo

Magnificent interview with quantum physicist Carlo Rovelli, where he dwells on what is Science and his passion with the pre-Socratic philosopher Anaximander:  

Let me tell you a story to explain what I mean. The story is an old story about my latest, greatest passion outside theoretical physics: an ancient scientist, or so I would say, even if often he is called a philosopher: Anaximander. […]

Until him, all the civilizations of the planet, everybody around the world, thought that the structure of the world was: the sky over our heads and the earth under our feet. There’s an up and a down, heavy things fall from the up to the down, and that’s reality. Reality is oriented up and down, heaven’s up and earth is down. Then comes Anaximander and says: no, is something else. ‘The earth is a finite body that floats in space, without falling, and the sky is not just over our head; it is all around.’ […]

How he gets it? Well obviously he looks at the sky, you see things going around, the stars, the heavens, the moon, the planets, everything moves around and keeps turning around us. […] nobody else got to this simple realization that the sky is not just over our head, it’s also under our feet. Why?

Because obviously it’s easy to suggest that the earth sort of floats in nothing, but then you have to answer the question: why doesn’t it fall? The genius of Anaximander was to answer this question…_

How? Well, you can either watch the interview or read the transcript… If you need some context on Anaximander, I suggest The History of Philosophy Without Any Gaps podcast on him:

http://www.historyofphilosophy.net/anaximander-anaximines 

via http://scipsy.tumblr.com/

http://edge.org/conversation/a-philosophy-of-physics

FDA and medical smartphone apps

FDA and medical smartphone apps

From the article:

…federal regulators lurched into action a year ago, offering their thinking on how to police this vast new frontier. Just as they were putting the finishing touches on a plan, lawmakers intervened. The Senate moved to put the plan on hold after tech firms convinced lawmakers that more government oversight would stifle innovation and cost jobs.

“There are two completely different mindsets,” said Merrill Matthews, a resident scholar at the Institute for Policy Innovation. “The app people think: Where is there a need and how do I fill it? And the FDA thinks: Where is there a problem and how can I control it?”

There’s a fine balance between a regulation free, wild wild west scenario and the stupidity which is our patent, trademark, and copyright system. It’s true that the mobile tech space moves way too fast for an agency like the FDA. However, I guarantee, the first person that gets hurt from a medical app is going to sue everyone under the sun and blame the government for not protecting the average Joe/Jane.

#ScienceEveryday  

http://www.chicagotribune.com/business/ct-biz-0626-health-apps-20120626,0,4426493.story

Blue for you or Pretty in Pink?

Blue for you or Pretty in Pink?

About  week ago I posted some pictures of my Hydrangeas that were just starting to bloom. http://goo.gl/Gn47h  I noticed that on the same plant, some of the flowers were blue and others were pink. I knew that pH played a role but I found out that it is actually the aluminum in the soil that make the blue pigment possible. So for ScienceSunday curated by Allison Sekuler Rajini Rao Robby Bowles and me, I had to dig up more info to post along with pictures from today.

When the pH is acidic, aluminum in the soil, mostly from clay, allows a metal complex of aluminum and a anthocyanin, named delphinidin 3-monoglucoside, to form. After the pictures, the first figure is of the aluminum complex. The next figure shows various blue flowers with sections cut revealing the pigment cells and protoplasts.

Although the next two figures are about Morning glories, they were too interesting to pass up. A certain ScienceSunday co-curator always has her eyes on certain channels. Similar to the previous figure, there is a cross section-cut revealing the pigmented cells. However, the paper and figure go on to discuss how the Morning glory does not have metal complexation. The petal color changes during flower opening due to pH changes which were measured in the second part of the figure. The final figure show the purported ion channel mechanism.

Plants can be beautiful. When you throw in a dash of science, they can be beautiful and intriguing.

Edit I forgot to add that a lot of insects leave hydrangeas alone. Why? Aluminum toxicity – win – win for us gardeners.

Sources: 

Kumi Yoshida ,  Mihoko Mori and Tadao Kondo

Nat. Prod. Rep., 2009,26, 884-915

DOI: 10.1039/B800165K http://goo.gl/VGlZH

http://goo.gl/CcFg6

So is it Men At Work – Blue For You (1983) or The Psychedelic Furs – Pretty In Pink ?

#ScienceSunday #ScienceEveryday

Hey scientist, smile!

Hey scientist, smile!

Note to self: smile more often. This reminds me of one day my sister called and said my 9 yr old nephew had a question. He wanted to know if scientists read and how much do they have to read. I told him that I read everyday and that it is very important for my job. He said he wants to grow up to be a scientist and so he will work on reading at school. He said it so begrudgingly, though. Altogether now, awwwww. I also recall the Fermi Lab experiment they describe in the post.

#ScienceSunday  and #ScienceEveryday  

Originally shared by Joanne Manaster

Why the Scientist Stereotype is Bad for Everyone, Especially Kids, http://www.wired.com/wiredscience/2012/06/opinion-scientist-stereotype/ #sciencesunday  +ScienceEveryday 

http://www.wired.com/wiredscience/

Make up your mind

Make up your mind

Most gardeners know that pH affects whether your Hydrangea will flower blue or pink. Did you know that the pH is affecting the availability of aluminum, in particular? Aluminum in the soil is made available for the blue pigment when the soil is acidic. From the USDA:

Flower color in H. macrophylla is dependent on cultivar and aluminum availability. Aluminum is necessary to produce the blue pigment for which bigleaf hydrangea is noted. Most garden soils have adequate aluminum, but the aluminum will not be available to the plant if the soil pH is high. For most bigleaf hydrangea cultivars, blue flowers will be produced in acidic soil (pH 5.5 and lower), whereas neutral to alkaline soils (pH 6.5 and higher) will usually produce pink flowers. Between pH 5.5 and pH 6.5, the flowers will be purple (see image at left) or a mixture of blue and pink flowers will be found on the same plant.

http://goo.gl/yvKtS

Enjoy the rest of my flowers/plants and Tame Impala.

Tame Impala – Why Won’t You Make Up Your Mind? (Erol Alkan Rework)

#ScienceEveryday

What’s buggin’ you?

What’s buggin’ you?

On NPR they discussed the first catalog of bacteria, viruses, and other microorganisms that are in and on our bodies. I read somewhere that the microbes on are body along with our diet help make our smell unique, at least that’s what helps dogs identify us by. I need to find a link for that. This part blew me away:

Scientists have already discovered some intriguing clues. For example, the microbes in a pregnant woman’s birth canal start to change just before she gives birth. Scientists think that’s so their babies are born with just the right microbiome they’ll need to live long, healthy lives.

#ScienceEveryday

http://www.npr.org/blogs/health/2012/06/13/154913334/finally-a-map-of-all-the-microbes-on-your-body

Kinect technology with surgeons

Kinect technology with surgeons

I’ve said elsewhere (http://goo.gl/W57jX), don’t count M$ out, just because the Windows phone isn’t taking off. Keep in mind their hands have been tied for some time due to the DoJ consent decree. The Kinect technology is just scratching the surface of what is possible. In the linked article, surgeons can use Kinect to manipulate images while maintaining sterility and not worry about miscommunication with techs (who previously would have manipulated the images). Remember Minority Report?

#ScienceSunday  curated by Allison Sekuler Rajini Rao and Robby Bowles 

http://news.cnet.com/8301-11386_3-57445827-76/surgeons-use-kinect-tech-during-aneurysm-procedures/