Endangered Elements

Endangered Elements

See helium in the top right corner? Helium is important for MRI and MRI is important to literally see what’s wrong with people. Think about it before buying a helium filled balloon. I wrote more about the helium reserve here:

https://plus.google.com/u/0/+ChadHaney/posts/99SpR28xBme

Originally shared by Compound Interest

Today’s post is a collaboration with the American Chemical Society’s Green Chemistry Institute, looking at some of the ‘endangered’ elements on the periodic table. Learn more about them here: http://wp.me/p4aPLT-1o4

Cancer Immunotherapy HOA in a few minutes

Cancer Immunotherapy HOA in a few minutes

It’s a hot topic in the news and you’ll learn what’s really going on. I plan on a follow up with a colleague from the Mayo Clinic so stay tuned.

Originally shared by Science on Google+

What does the immune system have to do with cancer? What exactly is immunotherapy? Join us for a Cancer Research UK and Science on Google+ Hangout on Air as we speak to Professor Frances Balkwill and Professor Ben Willcox about cancer immunotherapy. 

Fran is a Professor of Cancer Biology at Queen Mary University in London and is a fantastic science communicator. Her research focuses on the links between cancer and inflammation. Ben is a Professor of Molecular Immunology at the University of Birmingham and his work focuses on understanding immune receptor recognition. 

 

This HOA will be hosted by Dr Buddhini Samarasinghe  and Dr Kat Arney . You can tune in on Friday July 24th at 4 PM UK time. The hangout will be available for viewing on our YouTube channel (https://www.youtube.com/ScienceHangouts) after the event.

Smart conservation

Smart conservation

Another #ScienceEveryday  meets #Caturday . Conservationists were able to determine if endangered Iberian lynxes were pregnant or not by getting blood samples from triatominae, aka assassin bugs. Read the short lynx to find out more.

http://www.smithsonianmag.com/smart-news/how-do-you-give-iberian-lynx-pregnancy-test-use-assassin-bug-180955879/?utm_source=twitter.com&utm_medium=socialmedia

Do you even science bro?

Do you even science bro?

I can’t tell you how much I f#!&ing love this article from The Allium. I even read the title.

Thanks to Rajini Rao for pointing me to The Allium.

ETA

I should mention the Do you even science bro? joke is from Nic Hammond  from this post.

https://plus.google.com/u/0/+ChadHaney/posts/97yKScnyDU5

http://www.theallium.com/science-life/undergrad-student-didnt-even-understand-ifl-science-article-she-just-shared/

Yes cephalopods can be cute.

Yes cephalopods can be cute.

I would vote for Opisthoteuthis Adorablisis. I need to make a trip to Monterey Bay Aquarium next time I visit my dad. Make sure you watch the video unless you already know what an oviducal gland is.

#ScienceEveryday  

Originally shared by Monterey Bay Aquarium Research Institute (MBARI)

What do you call a tiny octopus with big eyes, gelatinous skin and is cute as a button? Nobody knows quite yet! Stephanie Bush of MBARI aims to classify and name this presently undescribed deep-sea cephalopod using preserved specimens and a clutch of eggs housed at the Monterey Bay Aquarium.

#‎CephalopodWeek‬ starts Friday! Stay tuned for 8 whole days of cephalopods!!! Watch this video from Science Friday about Stephanie Bush’s research:

http://www.sciencefriday.com/video/06/15/2015/isn-t-this-octopus-adorabilis.html

Moringa oleifera Seeds can clean water

Moringa oleifera Seeds can clean water

Dr. Stephanie Velegol and colleagues recently published their work on explaining how a protein from the seeds of the Moringa oleifera tree can kill bacteria. It was known for some time that women in Egypt would use the seeds to clean dirty water. Since modern filtration systems are expensive and difficult to get to rural areas, understanding how the Moringa oleifera seeds work is important. Using cryo-TEM and simulations (among other techniques), they were able to demonstrate how the Moringa oleifera cationic protein (MOCP) kills bacteria. It fuses the inner and outer bacteria membranes.

☼ cryogenic electron microscopy (cryo-EM)

Cryo-EM (transmission EM in this case) is a technique where the sample is cryogenically frozen and then sliced for the EM scope. There are two main types of EM: transmission and scanning. In transmission EM, the electrons go through the sample. In scanning EM the electrons go over the sample. Unlike optical (common) microscopes, EM, as you probably guessed, use electrons instead of light. You can read more here:

http://www.explainthatstuff.com/electronmicroscopes.html

☼ Simulations

Using data from multiple techniques, the researchers simulated what was going on with the MOCP and a test bacteria, E. coli. The data suggest that the MOCP cause flocculation and fusion of the inner and outer membranes.  Within 50 seconds the MOCP cause flocculation (like aggregation) of the bacteria. The simulations also suggest how the structure of the MOCP functions during the fusion process.

You can read the news blurb from Penn State here:

http://goo.gl/Bv4UkA

The full article is here (behind a paywall).

The Flocculating Cationic Polypetide from Moringa oleifera Seeds Damages Bacterial Cell Membranes by Causing Membrane Fusion.

Shebek K, Schantz AB, Sines I, Lauser K, Velegol S, Kumar M.

Langmuir. 2015 Apr 21;31(15):4496-502. doi: 10.1021/acs.langmuir.5b00015. Epub 2015 Apr 10.

http://www.ncbi.nlm.nih.gov/pubmed/25845029

#ScienceSunday  

h/t Gnotic Pasta and rasha kamel 

I’m glad my friends like Buddhini Samarasinghe​​​, Rajini Rao​​​, and Allison Sekuler​​​ are Tweeting away about how…

I’m glad my friends like Buddhini Samarasinghe​​​, Rajini Rao​​​, and Allison Sekuler​​​ are Tweeting away about how wrong Dr. Hunt is. I hope to catch Buddhini on BBC Radio.

ETA Nice fake apology. 

ETA 2 Here’s more from Buddhini

https://plus.google.com/+BuddhiniSamarasinghe/posts/arRaTcZSd8s

https://www.google.com/url?sa=t&source=web&rct=j&ei=UFZ4VdT3MYWMyATv34CQCA&url=http://www.cbc.ca/news/world/tim-hunt-nobel-prize-winner-apologizes-for-comments-about-women-in-labs-1.3107375&ved=0CDEQFjAGahUKEwjU38qYt4XGAhUFBpIKHe8vAII&usg=AFQjCNG8As0CL8IvbKnT28CPcAlJGmbkug&sig2=f0nUR6TRN3E0GwY_nrF7Dw

Taimyr wolf and the origins of dog

Taimyr wolf and the origins of dog

There’s an ongoing debate about where and when dogs originated. The when part might be closer to an answer now. Genetic drift is used by evolutionary biologist to try to recreate the lineage of species. The discovery of a 35,000-year-old wolf rib bone in the Taimyr peninsula in northern Siberia was the key to this story. The DNA from that bone suggests that it diverged from a common ancestor of present-day wolves and dogs near the beginning of the domestic dog lineage. Their technique uses genetic drift of ‘regular’ DNA and mitochondrial DNA.

► Genetic Drift

There are non-lethal random mutations in DNA that survive to the next generation due to natural selection and sometimes due to ‘luck’. Surviving by natural selection makes sense, a mutation affords an advantage so that offspring should excel and survive. Genetic drift is when a mutation doesn’t necessarily result in an advantage but is nevertheless passed on ‘by chance’. Tracing these mutations help create a lineage for evolutionary biologists.

► Mitochondrial DNA vs. Nuclear DNA

Mitochondria are the energy power plants inside cells. They have a few genes necessary for oxidative phosphorylation, which is a fancy term for making energy. The nucleus of the cell is where the chromosomes are. Nuclear DNA is the DNA that you hear about in the news, for example in forensic science. In the figure below, you can see that mitochondrial DNA is passed on only by the mother while nuclear DNA is passed along by both parents. Genetic drift in mitochondrial DNA is much slower and helps refine the lineage of a species. It is slower because it is only inherited by half of the genetic source, i.e., the mother.

You can read a summary of the article in layman’s terms here:

Arctic find confirms ancient origin of dogs

http://news.sciencemag.org/biology/2015/05/arctic-find-confirms-ancient-origin-dogs

Full article and source of the very cool graphical abstract:

Ancient Wolf Genome Reveals an Early Divergence of Domestic Dog Ancestors and Admixture into High-Latitude Breeds

Skoglund et al

Current Biology May 2015

http://www.cell.com/current-biology/abstract/S0960-9822(15)00432-7

Source for the mitochondria DNA figures:

University of California Museum of Paleontology’s Understanding Evolution (http://evolution.berkeley.eduhttp://goo.gl/WZgKRV

A bit more reading:

How the wolf became the dog (full article behind paywall)

http://news.sciencemag.org/environment/2015/04/how-wolf-became-dog

Late for #FidoFriday  but always on time for #ScienceEveryday